SOLVED: Mutation: selection balance: Consider a highly deleterious mutation that cuts the survival probability in half. The frequency is estimated to be about 5 copies per 3,000 wildtype alleles (3.3 x 10^-3).
SOLVED: The equilibrium frequencies under mutation-selection balance are as follows: Deleterious allele recessive: p^2 and q^2 Deleterious allele dominant: 2pq A very small selection coefficient (s=0.01) is active against an allele (A):